Factor X deficiency Causes and Treatment

Factor X deficiency is a bleeding disorder or when there is not enough protein in blood, factor X plays an important role in blood clotting, known as coagulation. Factor X deficiency can be genetic defect so it can be inherited from the victim family, it is also known as Stuart-Power factor deficiency. This can also be acquired; acquired factor X deficiency can be caused by many liver diseases or due to vitamin K deficiency or any anticoagulant drug.

Sign and Symptoms of Factor-X

 Depending on how much protein, blood carries, factor X deficiencies can be mild, moderate or severe. Nose bleeding, bleeding from the mouth, excessive bleeding during or after trauma may be considered as mild X-factor symptoms. Joint bleeding, muscles bleeding, gastrointestinal bleeding are considered to be more severe symptoms of X-factors. There are certain symptoms which indicate the seriousness of the diseases includes sudden bleeding in the brain and bleeding into the spinal cord. Pregnant women with the deficiency may experience of heavy bleeding during menstruation and at a high risk of miscarriage during the first trimester and suffer from the severe bleeding during and after the baby birth.

Diagnosis of Factor – X

Factor X assay is a blood test; this test is done to measure the activity of factor X in the blood. During this test a needle is need to be inserted to take out the blood which may cause slight pricking or stinging which may goes away after some time. Prothrombin time test is used to determine that how long plasma takes to clot. It measure the response of some of the coagulation factors, like factor X. There is another test called partial thromboplastin time which also determines the clotting time but it measure those factors which are not covered by the Prothrombin time test. Thrombin time test done to evaluates how long it takes two specific coagulation factors to interact and form a clot.

Treatment of Factor X deficiency

 According to the U.S food and drug administration, in 2015; factor X concentrate called Coagadex. This drug is used to treat inherited factor X deficiency. It is the first hormonal replacement therapy use to treat factor X deficiency. Treatment of factor X deficiency is generally is based on managing the symptoms and prevention of complications. For person with mild cut can be treated by cleaning and putting bandage. Eating well balanced diet, maintaining normal weight and take enough sleep are some of the measures can be taken to avoid the risk of uncontrolled bleeding. There is some anti platelet drugs such as aspirin, prevent blood clotting so the person who is suffering from the factor X deficiency should avoid such medicine to take as a headache reliever medicine. People with Factor-X deficiency should avoid the sports which may cause bleeding. Protective gear is always recommended for the children who are suffering from Factor-X deficiency.

 Other than this Sometime surgery or injection of vitamin K is also suggested by doctors depends on the cause and seriousness of the problem. Blood transfusion is another method, in this patient can receive blood from the other person.


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